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Hearing analysis in heterozygous and homozygous klotho gene deficient mice
OBJECTIVE: To understand the crucial role of the klotho gene in hearing development in mouse models. METHODS: PCR was used to identify CBA mice with different genotypes, i.e. WT, heterozygous (klotho +/−) or homozygous (klotho −/−). Mice phenotype and weight were recorded postnatal 25 days (P-25) an...
Autores principales: | Yuan, Na, Qiu, Shiwei, Wang, Qian, Zhuang, Wei, Li, Guoping, Sun, Tiantian, Yang, Shiming, Qiao, Yuehua, Shi, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese PLA General Hospital
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335471/ https://www.ncbi.nlm.nih.gov/pubmed/30671089 http://dx.doi.org/10.1016/j.joto.2018.04.001 |
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