Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool

DACH1 abundance is reduced in human malignancies, including breast cancer. Herein DACH1 was detected among multipotent fetal mammary stem cells in the embryo, among mixed lineage precursors, and in adult basal cells and (ERα(+)) luminal progenitors. Dach1 gene deletion at 6 weeks in transgenic mice...

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Detalles Bibliográficos
Autores principales: Jiao, Xuanmao, Li, Zhiping, Wang, Min, Katiyar, Sanjay, Di Sante, Gabriele, Farshchian, Mehdi, South, Andrew P., Cocola, Cinzia, Colombo, Daniele, Reinbold, Rolland, Zucchi, Ileana, Wu, Kongming, Tabas, Ira, Spike, Benjamin T., Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335505/
https://www.ncbi.nlm.nih.gov/pubmed/30554919
http://dx.doi.org/10.1016/j.stemcr.2018.11.010

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