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Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML

Relapse of acute myeloid leukemia (AML) remains a significant clinical challenge due to limited therapeutic options and poor prognosis. Leukemic stem cells (LSCs) are the cellular units responsible for relapse in AML, and strategies that target LSCs are thus critical. One proposed potential strategy...

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Detalles Bibliográficos
Autores principales:	Velasco-Hernandez, Talia, Soneji, Shamit, Hidalgo, Isabel, Erlandsson, Eva, Cammenga, Jörg, Bryder, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335588/ https://www.ncbi.nlm.nih.gov/pubmed/30595549 http://dx.doi.org/10.1016/j.stemcr.2018.11.023

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