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A randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck cancer
BACKGROUND: Cisplatin-induced hearing loss is frequent and severe. Antioxidants such as sodium thiosulfate (STS) can neutralize the effects of cisplatin. The objective of the trial was to test the efficacy of trans-tympanic injections of a STS gel to prevent cisplatin-induced ototoxicity. METHODS: E...
Autores principales: | Rolland, Viannique, Meyer, François, Guitton, Matthieu J., Bussières, Richard, Philippon, Daniel, Bairati, Isabelle, Leclerc, Mathieu, Côté, Mathieu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335693/ https://www.ncbi.nlm.nih.gov/pubmed/30651130 http://dx.doi.org/10.1186/s40463-019-0327-x |
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