A randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck cancer

BACKGROUND: Cisplatin-induced hearing loss is frequent and severe. Antioxidants such as sodium thiosulfate (STS) can neutralize the effects of cisplatin. The objective of the trial was to test the efficacy of trans-tympanic injections of a STS gel to prevent cisplatin-induced ototoxicity. METHODS: E...

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Detalles Bibliográficos
Autores principales: Rolland, Viannique, Meyer, François, Guitton, Matthieu J., Bussières, Richard, Philippon, Daniel, Bairati, Isabelle, Leclerc, Mathieu, Côté, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335693/
https://www.ncbi.nlm.nih.gov/pubmed/30651130
http://dx.doi.org/10.1186/s40463-019-0327-x

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