Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury

BACKGROUND: Microglia, the resident immune cells of the brain, exhibit various morphologies that correlate with their functions under physiological and pathological conditions. In conditions such as aging and stress, microglia priming occurs, which leads to altered morphology and lower threshold for...

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Detalles Bibliográficos
Autores principales: DiBona, Victoria L., Zhu, Wenxin, Shah, Mihir K., Rafalia, Aditi, Ben Cheikh, Hajer, Crockett, David P., Zhang, Huaye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335724/
https://www.ncbi.nlm.nih.gov/pubmed/30654821
http://dx.doi.org/10.1186/s12974-018-1390-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335724/
https://www.ncbi.nlm.nih.gov/pubmed/30654821
http://dx.doi.org/10.1186/s12974-018-1390-3

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