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Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury
BACKGROUND: Microglia, the resident immune cells of the brain, exhibit various morphologies that correlate with their functions under physiological and pathological conditions. In conditions such as aging and stress, microglia priming occurs, which leads to altered morphology and lower threshold for...
Autores principales: | DiBona, Victoria L., Zhu, Wenxin, Shah, Mihir K., Rafalia, Aditi, Ben Cheikh, Hajer, Crockett, David P., Zhang, Huaye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335724/ https://www.ncbi.nlm.nih.gov/pubmed/30654821 http://dx.doi.org/10.1186/s12974-018-1390-3 |
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