Cargando…

Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21

BACKGROUND: The mechanism of pancreatic cancer metastasis remains poorly understood. Recently, lncRNA CASC2 has been demonstrated to be a tumor suppressor in various types of cancer. This study aimed to explore the mechanism of CASC2 in the regulation of pancreatic cancer metastasis. METHODS: The ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hui, Feng, Xielin, Zhang, Mingyi, Liu, Aixiang, Tian, Lang, Bo, Wentao, Wang, Haiqing, Hu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335738/ https://www.ncbi.nlm.nih.gov/pubmed/30675129 http://dx.doi.org/10.1186/s12935-019-0728-y

Ejemplares similares

CircCASC15-miR-100-mTOR may influence the cervical cancer radioresistance
por: Yao, Tingting, et al.
Publicado: (2022)

Terlipressin in the treatment of hepatorenal syndrome: A systematic review and meta-analysis
por: Wang, Haiqing, et al.
Publicado: (2018)

Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy
por: Wang, Haiqing, et al.
Publicado: (2018)

Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis
por: He, Tianyu, et al.
Publicado: (2017)

Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma
por: Huo, Zirong, et al.
Publicado: (2021)

Long non-coding RNA UCA1 promotes breast cancer by upregulating PTP1B expression via inhibiting miR-206
por: Li, Yi, et al.
Publicado: (2019)

LncRNA LINC00337 sponges mir-1285-3p to promote proliferation and metastasis of lung adenocarcinoma cells by upregulating YTHDF1
por: Zhang, Ru-nan, et al.
Publicado: (2021)

LncRNA CASC15 upregulates cyclin D1 by downregulating miR-365 in laryngeal squamous cell carcinoma to promote cell proliferation
por: Zhu, Minhui, et al.
Publicado: (2022)

MiR-4310 induced by SP1 targets PTEN to promote glioma progression
por: Wu, Zhiyong, et al.
Publicado: (2020)

MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
por: Yang, Ting-Song, et al.
Publicado: (2013)

Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma
por: Sassenberg, Madeleine, et al.
Publicado: (2019)

Circ_0000140 restrains the proliferation, metastasis and glycolysis metabolism of oral squamous cell carcinoma through upregulating CDC73 via sponging miR-182-5p
por: Guo, Jia, et al.
Publicado: (2020)

CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression
por: Liu, Yi, et al.
Publicado: (2021)

Long non-coding RNA LINC01426 facilitates glioblastoma progression via sponging miR-345-3p and upregulation of VAMP8
por: Cao, Jingwei, et al.
Publicado: (2020)

Long non-coding RNA SNHG22 facilitates the malignant phenotypes in triple-negative breast cancer via sponging miR-324-3p and upregulating SUDS3
por: Fang, Xuan, et al.
Publicado: (2020)

ADAM17 promotes the invasion of hepatocellular carcinoma via upregulation MMP21
por: Xiang, Yuqi, et al.
Publicado: (2020)

Downregulation of microRNA-21 inhibited radiation-resistance of esophageal squamous cell carcinoma
por: Li, Fang, et al.
Publicado: (2018)

The Role of CASC2 and miR-21 Interplay in Glioma Malignancy and Patient Outcome
por: Skiriute, Daina, et al.
Publicado: (2020)

LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis
por: Wu, Liangcai, et al.
Publicado: (2020)

The lncRNA NEAT1 promotes the epithelial-mesenchymal transition and metastasis of osteosarcoma cells by sponging miR-483 to upregulate STAT3 expression
por: Chen, Yan, et al.
Publicado: (2021)

Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN–AKT axis
por: Coronel-Hernández, Jossimar, et al.
Publicado: (2019)

lncRNA CASC2 downregulation participates in rheumatoid arthritis, and CASC2 overexpression promotes the apoptosis of fibroblast-like synoviocytes by downregulating IL-17
por: Liu, Cheng, et al.
Publicado: (2020)

LINC01089 functions as a ceRNA for miR-152-3p to inhibit non‐small lung cancer progression through regulating PTEN
por: Zhang, Huixian, et al.
Publicado: (2021)

LncRNA CASC 2 is upregulated in aphthous stomatitis and predicts the recurrence
por: Lu, Jiaping, et al.
Publicado: (2020)

miR-429 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by downregulation of TLN1
por: Wang, Zhihui, et al.
Publicado: (2019)

LncRNA CASC15 is Upregulated in Osteosarcoma Plasma Exosomes and CASC15 Knockdown Inhibits Osteosarcoma Progression by Regulating miR-338-3p/RAB14 Axis
por: Zhang, Hongliang, et al.
Publicado: (2020)

The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer
por: Ma, Lixin, et al.
Publicado: (2019)

The Long Non-Coding RNA CASC2 Suppresses Cell Viability, Migration, and Invasion in Hepatocellular Carcinoma Cells by Directly Downregulating miR-183
por: Sun, Jian, et al.
Publicado: (2019)

Long non-coding RNA MIAT promotes growth and metastasis of colorectal cancer cells through regulation of miR-132/Derlin-1 pathway
por: Liu, Zhaoxia, et al.
Publicado: (2018)

Overexpression of CBS/H(2)S inhibits proliferation and metastasis of colon cancer cells through downregulation of CD44
por: Zhang, Yuyang, et al.
Publicado: (2022)

CASC8 lncRNA Promotes the Proliferation of Retinoblastoma Cells Through Downregulating miR34a Methylation
por: Yang, Bo, et al.
Publicado: (2020)

Long non-coding RNA FER1L4 inhibits prostate cancer progression via sponging miR-92a-3p and upregulation of FBXW7
por: Huo, Wei, et al.
Publicado: (2020)

Effect of Benzothiazole based conjugates in causing apoptosis by Regulating p53, PTEN and MAP Kinase proteins affecting miR-195a and miR-101-1
por: Pushpavalli, SNCVL, et al.
Publicado: (2011)

Long non-coding RNA CASC2 enhanced cisplatin-induced viability inhibition of non-small cell lung cancer cells by regulating the PTEN/PI3K/Akt pathway through down-regulation of miR-18a and miR-21
por: Li, Li, et al.
Publicado: (2018)

miR-363 suppresses the proliferation, migration and invasion of clear cell renal cell carcinoma by downregulating S1PR1
por: Xie, Yongpeng, et al.
Publicado: (2020)

MiR-519d facilitates the progression and metastasis of cervical cancer through direct targeting Smad7
por: Zhou, Jue-Yu, et al.
Publicado: (2016)

STAT3-Induced Upregulation of lncRNA CASC9 Promotes the Progression of Bladder Cancer by Interacting with EZH2 and Affecting the Expression of PTEN
por: Yuan, Bo, et al.
Publicado: (2020)

LINC01006 promotes cell proliferation and metastasis in pancreatic cancer via miR-2682-5p/HOXB8 axis
por: Zhang, Luyang, et al.
Publicado: (2019)

Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition
por: Wang, Jing, et al.
Publicado: (2015)

A Left-Sided Approach for Resection of Hepatic Caudate Lobe Hemangioma: Two Case Reports and a Literature Review
por: Feng, Xielin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_honkc1rnvl847k35fdadis4kcv