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Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial
BACKGROUND: Celecoxib is frequently prescribed to treat knee osteoarthritis (KOA), but how celecoxib influences the activity of the central nervous system to alleviate chronic pain remains unclear. METHODS: One hundred eight patients with KOA will be enrolled in this study. Patients will be allocate...
Autores principales: | Tang, Chenjian, Dong, Xiaohui, He, Wenhua, Cheng, Shirui, Chen, Yang, Huang, Yong, Yin, Bao, Sheng, Yu, Zhou, Jun, Wu, Xiaoli, Zeng, Fang, Li, Zhengjie, Liang, Fanrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335784/ https://www.ncbi.nlm.nih.gov/pubmed/30651138 http://dx.doi.org/10.1186/s13063-018-3111-8 |
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