Chimeric tumor modeling reveals role of partial PDL1 expression in resistance to virally induced immunotherapy

Expression of PDL1 on the surface of tumor cells can blunt the efficacy of many cancer immunotherapies. For example, our lab has previously shown that tumors derived from malignant cells incapable of expressing PDL1 are highly susceptible to immunotherapy induced by oncolytic virus treatment while t...

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Detalles Bibliográficos
Autores principales: Bartee, Mee Y., Dryja, Parker C., Bartee, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335801/
https://www.ncbi.nlm.nih.gov/pubmed/30651147
http://dx.doi.org/10.1186/s40425-018-0496-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335801/
https://www.ncbi.nlm.nih.gov/pubmed/30651147
http://dx.doi.org/10.1186/s40425-018-0496-6

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