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Chimeric tumor modeling reveals role of partial PDL1 expression in resistance to virally induced immunotherapy
Expression of PDL1 on the surface of tumor cells can blunt the efficacy of many cancer immunotherapies. For example, our lab has previously shown that tumors derived from malignant cells incapable of expressing PDL1 are highly susceptible to immunotherapy induced by oncolytic virus treatment while t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335801/ https://www.ncbi.nlm.nih.gov/pubmed/30651147 http://dx.doi.org/10.1186/s40425-018-0496-6 |