Cargando…

Long non-coding RNA ANRIL-mediated inflammation response is involved in protective effect of rhein in uric acid nephropathy rats

BACKGROUND: The aim of this study was to investigate the role of long non-coding RNAs (LncRNAs) antisense non-coding RNA in the INK4 locus (ANRIL) in anti-inflammation of rhein in uric acid nephropathy (UAN) rats. METHODS: Rat models of UAN were induced by adenine and potassium oxonate. Enzyme-linke...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jiacai, Wang, Daochun, Wu, Hao, Yang, Zhijie, Yang, Na, Dong, Junjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335822/ https://www.ncbi.nlm.nih.gov/pubmed/30675335 http://dx.doi.org/10.1186/s13578-019-0273-3

Ejemplares similares

Protection of rhein on IgA nephropathy mediated by inhibition of fibronectin expression in rats
por: Sheng-Nan, Peng, et al.
Publicado: (2013)

Toll-like receptor 4 is involved in a protective effect of rhein on immunoglobulin A nephropathy
por: Chen, Xiaowen, et al.
Publicado: (2015)

The Molecular Mechanism of Rhein in Diabetic Nephropathy
por: Zeng, Cong-Cong, et al.
Publicado: (2014)

Rhein lysinate protects renal function in diabetic nephropathy of KK/HlJ mice
por: Lin, Ya-Jun, et al.
Publicado: (2017)

The Long Non-Coding RNA ANRIL in Cancers
por: Sanchez, Aymeric, et al.
Publicado: (2023)

ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy
por: Sooshtari, Parisa, et al.
Publicado: (2022)

ANRIL overexpression globally induces expression and alternative splicing of genes involved in inflammation in HUVECs
por: Wufuer, Alimu, et al.
Publicado: (2022)

The anti-obesity effects of rhein on improving insulin resistance (IR) and blood lipid levels are involved in endoplasmic reticulum stress (ERs), inflammation, and oxidative stress in vivo and vitro: The protective mechanism of rhein in preventing obesity
por: Ji, Li, et al.
Publicado: (2021)

circANRIL reduces vascular endothelial injury, oxidative stress and inflammation in rats with coronary atherosclerosis
por: Shi, Peixia, et al.
Publicado: (2020)

Effects of Rhein on Bile Acid Homeostasis in Rats
por: Xian, Zhong, et al.
Publicado: (2020)

The role of long non-coding RNA ANRIL in the development of atherosclerosis
por: Gareev, Ilgiz, et al.
Publicado: (2022)

Rhein protects against cerebral ischemic-/reperfusion-induced oxidative stress and apoptosis in rats
por: Zhao, Qipeng, et al.
Publicado: (2018)

Rhein Meeting Program
por: The HiLumi LHC Collaboration
Publicado: (2014)

The clinical significance of long non-coding RNA ANRIL level in diabetic retinopathy
por: Chen, ShuZe, et al.
Publicado: (2019)

The Role of ANRIL in Atherosclerosis
por: Razeghian-Jahromi, Iman, et al.
Publicado: (2022)

Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro
por: Ge, Hui, et al.
Publicado: (2017)

A Significant Association Between Rhein and Diabetic Nephropathy in Animals: A Systematic Review and Meta-Analysis
por: Hu, Heng-Chang, et al.
Publicado: (2019)

Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein
por: Wang, Li, et al.
Publicado: (2023)

Protective Effects of Rhubarb in Rats with Acute Pancreatitis and the Role of Its Active Compound Rhein on Mitochondria of Exocrine Cells
por: Zhao, Jianlei, et al.
Publicado: (2018)

Serum uric acid and diabetic nephropathy
por: Momeni, Ali
Publicado: (2012)

Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1 microdeletions
por: Mußotter, Tanja, et al.
Publicado: (2012)

Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
por: Holdt, Lesca M., et al.
Publicado: (2016)

Long Non-coding RNA ANRIL in the Nucleus Associates With Periostin Expression in Breast Cancer
por: Mehta-Mujoo, Paulomi M., et al.
Publicado: (2019)

Implication of repeat insertion domains in the trans-activity of the long non-coding RNA ANRIL
por: Alfeghaly, Charbel, et al.
Publicado: (2021)

Rhein: A Review of Pharmacological Activities
por: Zhou, Yan-Xi, et al.
Publicado: (2015)

Dr. Meyer L. Rhein’s Technique
por: Southwell, Charles
Publicado: (1904)

A Reply to Dr. Rhein’s Answer
por: Wedelstaedt, E. K.
Publicado: (1904)

Rhein exhibits antioxidative effects similar to Rhubarb in a rat model of traumatic brain injury
por: Xu, Xia, et al.
Publicado: (2017)

Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake
por: Wang, Guowei, et al.
Publicado: (2019)

Effects of an Astragalus Polysaccharide and Rhein Combination on Apoptosis in Rats with Chronic Renal Failure
por: Lian, Yonghong, et al.
Publicado: (2014)

Rhein antagonizes P2X(7) receptor in rat peritoneal macrophages
por: Hu, Fen, et al.
Publicado: (2015)

Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats
por: Chen, Yakun, et al.
Publicado: (2019)

Pharmacokinetics and Pharmacodynamics of the Combination of Rhein and Curcumin in the Treatment of Chronic Kidney Disease in Rats
por: He, Xiaoying, et al.
Publicado: (2020)

Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling
por: Tu, Yue, et al.
Publicado: (2017)

Downregulation of long non-coding RNA ANRIL suppresses lymphangiogenesis and lymphatic metastasis in colorectal cancer
por: Sun, Zhenqiang, et al.
Publicado: (2016)

Long Non-Coding RNA ANRIL as a Potential Biomarker of Chemosensitivity and Clinical Outcomes in Osteosarcoma
por: Lee, Adam M., et al.
Publicado: (2021)

Prognostic Significance of Long Non Coding RNA ANRIL and SNHG14 in Acute Myeloid Leukemia
por: Gamaleldin, Marwa A, et al.
Publicado: (2021)

Rhein-8-O-β-D-glucopyranoside inhibited high glucose-induced apoptosis of human mesangial cells by regulating the lincRNA ANRIL/let-7a/TGF-β1/Smad signaling pathway
por: Zhang, Lan-Sheng, et al.
Publicado: (2020)

Predicting new molecular targets for rhein using network pharmacology
por: Zhang, Aihua, et al.
Publicado: (2012)

Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia
por: Li, Rong-Rong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nsho3f4t6ih7a86bm5icnui78c