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Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities

BACKGROUND: Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cells enter the circulation to gain access to distant tissues, but how this fluid m...

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Detalles Bibliográficos
Autores principales:	Choi, Hye Yeon, Yang, Gwang-Mo, Dayem, Ahmed Abdal, Saha, Subbroto Kumar, Kim, Kyeongseok, Yoo, Youngbum, Hong, Kwonho, Kim, Jin-Hoi, Yee, Cassian, Lee, Kyung-Mi, Cho, Ssang-Goo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335853/ https://www.ncbi.nlm.nih.gov/pubmed/30651129 http://dx.doi.org/10.1186/s13058-018-1071-2

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