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The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?

Introduction: Although coronary tortuosity is relatively common in coronary angiograms, there is much debate over the significance of this anatomical variation. So in this study the relation between significant coronary tortuosity (SCT) and coronary artery disease (CAD) was examined. Methods: The cr...

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Autores principales: Khosravani-Rudpishi, Mohsen, Joharimoghadam, Adel, Rayzan, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335987/
https://www.ncbi.nlm.nih.gov/pubmed/30680079
http://dx.doi.org/10.15171/jcvtr.2018.36
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author Khosravani-Rudpishi, Mohsen
Joharimoghadam, Adel
Rayzan, Elham
author_facet Khosravani-Rudpishi, Mohsen
Joharimoghadam, Adel
Rayzan, Elham
author_sort Khosravani-Rudpishi, Mohsen
collection PubMed
description Introduction: Although coronary tortuosity is relatively common in coronary angiograms, there is much debate over the significance of this anatomical variation. So in this study the relation between significant coronary tortuosity (SCT) and coronary artery disease (CAD) was examined. Methods: The cross-sectional study included 737 patients (57% male) who were admitted to the hospital for a coronary angiography, based on their symptoms or non-invasive imaging. Coronary arteries defined as SCT are in the presence of either ≥3 consecutive curvatures of 90◦ to 180◦ or ≥2 consecutive curvatures of ≥180◦ measured at the end-diastole, in a major epicardial coronary artery ≥2 mm in diameter. Results: 29.17% of the patients had SCT of which females (64.7% vs. 34.1%, P < 0.001) and higher aged persons (62.9±8.4 vs. 57.8±10.7 years ± SD; P < 0.001) were significantly associated with SCT compared to non-SCT. Left anterior descending artery (LAD), left circumflex artery (LCX) and right coronary artery (RCA) with SCT in comparison to non-SCT, had lesser probability of CAD with stenosis severity of ≥50% (34.5% vs. 46.1%; P = 0.019 and 17.7% vs. 31.1%; P = 0.001 and 27.9% vs. 43.5%; P = 0.013 respectively) and also had significant lower Gensini scores (4.1±5.3 vs. 8.4±11.9; P = 0.011; 2.1±3.4 vs. 5.2±9.5; P = 0.01 and 1.2±1.9 vs. 5.03±8.9; P < 0.001 respectively) but higher TIMI frame count (15.7±5.3 vs. 11.9±4.6; P < 0.001 and 17.1±4.4 vs. 12.7±4.4; P < 0.001 and 15.2±3.9 vs. 11.6±4.8; P < 0.001 respectively). Conclusion: SCT is negatively correlated with CAD and there is a significant association between SCT and reduced coronary flow rate.
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spelling pubmed-63359872019-01-24 The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation? Khosravani-Rudpishi, Mohsen Joharimoghadam, Adel Rayzan, Elham J Cardiovasc Thorac Res Original Article Introduction: Although coronary tortuosity is relatively common in coronary angiograms, there is much debate over the significance of this anatomical variation. So in this study the relation between significant coronary tortuosity (SCT) and coronary artery disease (CAD) was examined. Methods: The cross-sectional study included 737 patients (57% male) who were admitted to the hospital for a coronary angiography, based on their symptoms or non-invasive imaging. Coronary arteries defined as SCT are in the presence of either ≥3 consecutive curvatures of 90◦ to 180◦ or ≥2 consecutive curvatures of ≥180◦ measured at the end-diastole, in a major epicardial coronary artery ≥2 mm in diameter. Results: 29.17% of the patients had SCT of which females (64.7% vs. 34.1%, P < 0.001) and higher aged persons (62.9±8.4 vs. 57.8±10.7 years ± SD; P < 0.001) were significantly associated with SCT compared to non-SCT. Left anterior descending artery (LAD), left circumflex artery (LCX) and right coronary artery (RCA) with SCT in comparison to non-SCT, had lesser probability of CAD with stenosis severity of ≥50% (34.5% vs. 46.1%; P = 0.019 and 17.7% vs. 31.1%; P = 0.001 and 27.9% vs. 43.5%; P = 0.013 respectively) and also had significant lower Gensini scores (4.1±5.3 vs. 8.4±11.9; P = 0.011; 2.1±3.4 vs. 5.2±9.5; P = 0.01 and 1.2±1.9 vs. 5.03±8.9; P < 0.001 respectively) but higher TIMI frame count (15.7±5.3 vs. 11.9±4.6; P < 0.001 and 17.1±4.4 vs. 12.7±4.4; P < 0.001 and 15.2±3.9 vs. 11.6±4.8; P < 0.001 respectively). Conclusion: SCT is negatively correlated with CAD and there is a significant association between SCT and reduced coronary flow rate. Tabriz University of Medical Sciences 2018 2018-12-13 /pmc/articles/PMC6335987/ /pubmed/30680079 http://dx.doi.org/10.15171/jcvtr.2018.36 Text en © 2018 The Author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Khosravani-Rudpishi, Mohsen
Joharimoghadam, Adel
Rayzan, Elham
The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title_full The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title_fullStr The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title_full_unstemmed The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title_short The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation?
title_sort significant coronary tortuosity and atherosclerotic coronary artery disease; what is the relation?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335987/
https://www.ncbi.nlm.nih.gov/pubmed/30680079
http://dx.doi.org/10.15171/jcvtr.2018.36
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