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The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease

Introduction: Coronary Artery Disease (CAD) is known as the major cause of morbidity and mortality in the world with a growing trend, especially in some developing countries. CAD commonly observed in elderly cases, however; recently it is usually found in young adults. In this study, we aimed to eva...

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Autores principales: Alishiri, Gholamhossein, Moshkani Farahani, Maryam, Sadr, Ali, Salesi, Mahmood, Rahemi, Mostafa, Rezapoor, Bahador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335990/
https://www.ncbi.nlm.nih.gov/pubmed/30680082
http://dx.doi.org/10.15171/jcvtr.2018.39
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author Alishiri, Gholamhossein
Moshkani Farahani, Maryam
Sadr, Ali
Salesi, Mahmood
Rahemi, Mostafa
Rezapoor, Bahador
author_facet Alishiri, Gholamhossein
Moshkani Farahani, Maryam
Sadr, Ali
Salesi, Mahmood
Rahemi, Mostafa
Rezapoor, Bahador
author_sort Alishiri, Gholamhossein
collection PubMed
description Introduction: Coronary Artery Disease (CAD) is known as the major cause of morbidity and mortality in the world with a growing trend, especially in some developing countries. CAD commonly observed in elderly cases, however; recently it is usually found in young adults. In this study, we aimed to evaluate the prevalence of anti-phospholipid antibody syndrome (APS) in patients with premature CAD. Methods: The cross-sectional study was conducted in Baqiyatallah hospital from April 2012 to April 2016. Patients with premature CAD were included in the study. The data regarding the laboratory tests, echocardiography, and angiography were obtained from all cases. Results: Overall 133 eligible patients were included in the study. In the first set of the laboratory test, 18 patients were recognized to have APS (13.53%). The second confirmatory APA test was showing 3 of 18 patients were considered to have APS (2.25%). Conclusion: The results showed there is an association between the risk of developing Premature CAD and APS could potentially. The APS may have significant effects on the risk of coronary heart disease, especially in young adults.
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spelling pubmed-63359902019-01-24 The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease Alishiri, Gholamhossein Moshkani Farahani, Maryam Sadr, Ali Salesi, Mahmood Rahemi, Mostafa Rezapoor, Bahador J Cardiovasc Thorac Res Original Article Introduction: Coronary Artery Disease (CAD) is known as the major cause of morbidity and mortality in the world with a growing trend, especially in some developing countries. CAD commonly observed in elderly cases, however; recently it is usually found in young adults. In this study, we aimed to evaluate the prevalence of anti-phospholipid antibody syndrome (APS) in patients with premature CAD. Methods: The cross-sectional study was conducted in Baqiyatallah hospital from April 2012 to April 2016. Patients with premature CAD were included in the study. The data regarding the laboratory tests, echocardiography, and angiography were obtained from all cases. Results: Overall 133 eligible patients were included in the study. In the first set of the laboratory test, 18 patients were recognized to have APS (13.53%). The second confirmatory APA test was showing 3 of 18 patients were considered to have APS (2.25%). Conclusion: The results showed there is an association between the risk of developing Premature CAD and APS could potentially. The APS may have significant effects on the risk of coronary heart disease, especially in young adults. Tabriz University of Medical Sciences 2018 2018-12-13 /pmc/articles/PMC6335990/ /pubmed/30680082 http://dx.doi.org/10.15171/jcvtr.2018.39 Text en © 2018 The Author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Alishiri, Gholamhossein
Moshkani Farahani, Maryam
Sadr, Ali
Salesi, Mahmood
Rahemi, Mostafa
Rezapoor, Bahador
The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title_full The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title_fullStr The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title_full_unstemmed The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title_short The frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
title_sort frequency of anti-phospholipid antibody syndrome in patients with premature coronary artery disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335990/
https://www.ncbi.nlm.nih.gov/pubmed/30680082
http://dx.doi.org/10.15171/jcvtr.2018.39
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