An adaptive population enrichment phase III trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma (TAPPAS trial)

BACKGROUND: Major challenges in clinical trials of ultra-orphan oncology diseases include limited patient availability and paucity of reliable prior data for estimating the treatment effect and, therefore, determining optimal sample size. Angiosarcoma (AS), a particularly aggressive form of soft tis...

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Detalles Bibliográficos
Autores principales: Mehta, C R, Liu, L, Theuer, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336002/
https://www.ncbi.nlm.nih.gov/pubmed/30357394
http://dx.doi.org/10.1093/annonc/mdy464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336002/
https://www.ncbi.nlm.nih.gov/pubmed/30357394
http://dx.doi.org/10.1093/annonc/mdy464

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