Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer

BACKGROUND: Invasive lobular carcinoma (ILC) as a disease entity distinct from invasive ductal carcinoma (IDC) has merited focused studies of the genomic landscape, but those to date are largely limited to the assessment of early-stage cancers. Given that genomic alterations develop as acquired resi...

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Detalles Bibliográficos
Autores principales: Sokol, E S, Feng, Y X, Jin, D X, Basudan, A, Lee, A V, Atkinson, J M, Chen, J, Stephens, P J, Frampton, G M, Gupta, P B, Ross, J S, Chung, J H, Oesterreich, S, Ali, S M, Hartmaier, R J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336006/
https://www.ncbi.nlm.nih.gov/pubmed/30423024
http://dx.doi.org/10.1093/annonc/mdy497

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