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High drug payload nanoparticles formed from dexamethasone-peptide conjugates for the treatment of endotoxin-induced uveitis in rabbit

PURPOSE: To develop and demonstrate the effectiveness of a novel dexamethasone (Dex) nanoformulation for treating uveitis. MATERIALS AND METHODS: We designed and screened a dexamethasone-peptide conjugate (Dex-SA-FFFE), formed via a biodegradable ester bond linkage, that could spontaneously form hig...

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Detalles Bibliográficos
Autores principales:	Yu, Xinxin, Zhang, Renshu, Lei, Lei, Song, Qianqian, Li, Xingyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336024/ https://www.ncbi.nlm.nih.gov/pubmed/30666116 http://dx.doi.org/10.2147/IJN.S179118

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