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Roles, function and relevance of LAG3 in HIV infection

HIV causes several forms of immune dysfunction that need to be addressed in a functional cure for HIV. Immune exhaustion describes a dysfunctional phenotype caused by chronic cellular activation. Lymphocyte activation gene-3 (LAG3) is one of several negative coreceptors known as immune checkpoints t...

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Detalles Bibliográficos
Autores principales: Graydon, Colin G., Balasko, Allison L., Fowke, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336228/
https://www.ncbi.nlm.nih.gov/pubmed/30653605
http://dx.doi.org/10.1371/journal.ppat.1007429

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