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Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis

Intestinal integrity is maintained by balanced numbers of CD103(+) Dendritic cells (DCs), which generate peripherally induced regulatory T cells (iTregs). We have developed a mouse model where DC-specific constitutive CD40 signals caused a strong reduction of CD103(+) DCs in the lamina propria (LP)...

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Detalles Bibliográficos
Autores principales:	Ogrinc Wagner, Ana, Friedrich, Verena, Barthels, Christian, Marconi, Peggy, Blutke, Andreas, Brombacher, Frank, Brocker, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336277/ https://www.ncbi.nlm.nih.gov/pubmed/30653608 http://dx.doi.org/10.1371/journal.pone.0210998

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