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Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients?
BACKGROUND: The incidence of acute myocardial infarction (AMI) in healthy patients undergoing noncardiac surgery is <1%. When patients with chronic kidney disease (CKD) undergo orthopedic surgery, AMI incidence can be expected to be relatively high. However, data on a population-wide scale is lac...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336305/ https://www.ncbi.nlm.nih.gov/pubmed/30653544 http://dx.doi.org/10.1371/journal.pone.0210554 |
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author | Lee, Thung-Lip Kao, Feng-Chen Hsu, Yao-Chun Lo, Ying-Ying Tu, Yuan-Kun |
author_facet | Lee, Thung-Lip Kao, Feng-Chen Hsu, Yao-Chun Lo, Ying-Ying Tu, Yuan-Kun |
author_sort | Lee, Thung-Lip |
collection | PubMed |
description | BACKGROUND: The incidence of acute myocardial infarction (AMI) in healthy patients undergoing noncardiac surgery is <1%. When patients with chronic kidney disease (CKD) undergo orthopedic surgery, AMI incidence can be expected to be relatively high. However, data on a population-wide scale is lacking. OBJECTIVE: To investigate AMI incidence in patients with CKD (with and without dialysis) undergoing orthopedic surgery. DESIGN: A population-based study covering the period from January 1, 1997, to December 31, 2011. SETTING: Data from the Taiwan National Health Insurance Research Database. PARTICIPANTS: Participants were 219,195 patients with CKD who underwent surgery between January 1, 1997, and December 31, 2011. RESULTS: AMI occurred in 2,708 participants (1.24%). The AMI incidence rate in the dialyzed group was 1.52%, which was higher than that in the nondialyzed group after propensity score matching. Dialysis (odds ratio [OR]: 1.79; 95% confidence interval [CI]: 1.62–1.98), male (OR: 1.42; 95% CI: 1.28–1.57), diabetes mellitus (OR: 1.61; 95% CI: 1.44–1.80), hyperlipidemia (OR: 1.88; 95% CI: 1.68–2.11), old myocardial infarction (OR: 18.87; 95% CI: 16.26–1.21.90), and cerebral vascular disease (CVA) (OR: 1.29; 95% CI: 1.30–1.47) were all associated with AMI in the patients with CKD. CONCLUSIONS: The AMI risk was higher in the patients with CKD undergoing orthopedic surgery than in the general population, and the dialyzed group had a higher risk of AMI than did the nondialyzed group. |
format | Online Article Text |
id | pubmed-6336305 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-63363052019-01-30 Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? Lee, Thung-Lip Kao, Feng-Chen Hsu, Yao-Chun Lo, Ying-Ying Tu, Yuan-Kun PLoS One Research Article BACKGROUND: The incidence of acute myocardial infarction (AMI) in healthy patients undergoing noncardiac surgery is <1%. When patients with chronic kidney disease (CKD) undergo orthopedic surgery, AMI incidence can be expected to be relatively high. However, data on a population-wide scale is lacking. OBJECTIVE: To investigate AMI incidence in patients with CKD (with and without dialysis) undergoing orthopedic surgery. DESIGN: A population-based study covering the period from January 1, 1997, to December 31, 2011. SETTING: Data from the Taiwan National Health Insurance Research Database. PARTICIPANTS: Participants were 219,195 patients with CKD who underwent surgery between January 1, 1997, and December 31, 2011. RESULTS: AMI occurred in 2,708 participants (1.24%). The AMI incidence rate in the dialyzed group was 1.52%, which was higher than that in the nondialyzed group after propensity score matching. Dialysis (odds ratio [OR]: 1.79; 95% confidence interval [CI]: 1.62–1.98), male (OR: 1.42; 95% CI: 1.28–1.57), diabetes mellitus (OR: 1.61; 95% CI: 1.44–1.80), hyperlipidemia (OR: 1.88; 95% CI: 1.68–2.11), old myocardial infarction (OR: 18.87; 95% CI: 16.26–1.21.90), and cerebral vascular disease (CVA) (OR: 1.29; 95% CI: 1.30–1.47) were all associated with AMI in the patients with CKD. CONCLUSIONS: The AMI risk was higher in the patients with CKD undergoing orthopedic surgery than in the general population, and the dialyzed group had a higher risk of AMI than did the nondialyzed group. Public Library of Science 2019-01-17 /pmc/articles/PMC6336305/ /pubmed/30653544 http://dx.doi.org/10.1371/journal.pone.0210554 Text en © 2019 Lee et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Lee, Thung-Lip Kao, Feng-Chen Hsu, Yao-Chun Lo, Ying-Ying Tu, Yuan-Kun Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title | Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title_full | Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title_fullStr | Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title_full_unstemmed | Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title_short | Perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: Is there any difference between dialyzed and nondialyzed patients? |
title_sort | perioperative acute myocardial infarction rate in chronic renal disease patients undergoing orthopedic surgery: is there any difference between dialyzed and nondialyzed patients? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336305/ https://www.ncbi.nlm.nih.gov/pubmed/30653544 http://dx.doi.org/10.1371/journal.pone.0210554 |
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