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Epitranscriptomics: Correlation of N(6)-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats

Internal RNA modifications have been known for decades, however their roles in mRNA regulation have only recently started to be elucidated. Here we investigated the most abundant mRNA modification, N(6)-methyladenosine (m(6)A) in transcripts from the hippocampus of HIV transgenic (Tg) rats. The dist...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Zorman, Barry, Sumazin, Pavel, Sanna, Pietro Paolo, Repunte-Canonigo, Vez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336335/
https://www.ncbi.nlm.nih.gov/pubmed/30653517
http://dx.doi.org/10.1371/journal.pone.0203566