The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1

The protein folding capacity of the endoplasmic reticulum (ER) is tightly regulated by a network of signaling pathways, known as the unfolded protein response (UPR). UPR sensors monitor the ER folding status to adjust ER folding capacity according to need. To understand how the UPR sensor IRE1 maint...

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Detalles Bibliográficos
Autores principales: Acosta-Alvear, Diego, Karagöz, G Elif, Fröhlich, Florian, Li, Han, Walther, Tobias C, Walter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336407/
https://www.ncbi.nlm.nih.gov/pubmed/30582518
http://dx.doi.org/10.7554/eLife.43036

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