N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria

J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cyst...

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Detalles Bibliográficos
Autores principales: Newton, Gerald L., Rawat, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336425/
https://www.ncbi.nlm.nih.gov/pubmed/30647158
http://dx.doi.org/10.1128/mBio.02634-18
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author Newton, Gerald L.
Rawat, Mamta
author_facet Newton, Gerald L.
Rawat, Mamta
author_sort Newton, Gerald L.
collection PubMed
description J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S-adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria.
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spelling pubmed-63364252019-01-25 N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria Newton, Gerald L. Rawat, Mamta mBio Commentary J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S-adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria. American Society for Microbiology 2019-01-15 /pmc/articles/PMC6336425/ /pubmed/30647158 http://dx.doi.org/10.1128/mBio.02634-18 Text en Copyright © 2019 Newton and Rawat. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Newton, Gerald L.
Rawat, Mamta
N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_full N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_fullStr N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_full_unstemmed N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_short N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_sort n-methyl-bacillithiol, a novel thiol from anaerobic bacteria
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336425/
https://www.ncbi.nlm.nih.gov/pubmed/30647158
http://dx.doi.org/10.1128/mBio.02634-18
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