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Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in β Cells
OBJECTIVES: Menin, a chromatin binding protein, interacts with various epigenetic regulators to regulate gene transcription, whereas forkhead box protein O1 (FOXO1) is a transcription factor that can be regulated by multiple signaling pathways. Both menin and FOXO1 are crucial regulators of β-cell f...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336489/ https://www.ncbi.nlm.nih.gov/pubmed/30629029 http://dx.doi.org/10.1097/MPA.0000000000001239 |