Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer

The role of the tumour-suppressor miR-34 family in breast physiology and in mammary stem cells (MaSCs) is largely unknown. Here, we revealed that miR-34 family, and miR-34a in particular, is implicated in mammary epithelium homoeostasis. Expression of miR-34a occurs upon luminal commitment and diffe...

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Detalles Bibliográficos
Autores principales: Bonetti, Paola, Climent, Montserrat, Panebianco, Fabiana, Tordonato, Chiara, Santoro, Angela, Marzi, Matteo Jacopo, Pelicci, Pier Giuseppe, Ventura, Andrea, Nicassio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336680/
https://www.ncbi.nlm.nih.gov/pubmed/30093634
http://dx.doi.org/10.1038/s41388-018-0445-3

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