O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit

Advanced colorectal cancer (CRC) is one of the deadliest cancers, and the 5-year survival rate of patients with metastasis is extremely low. The epithelial–mesenchymal transition (EMT) is considered essential for metastatic CRC, but the fundamental molecular basis underlying this effect remains unkn...

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Detalles Bibliográficos
Autores principales: Jiang, Mingzuo, Xu, Bing, Li, Xiaowei, Shang, Yulong, Chu, Yi, Wang, Weijie, Chen, Di, Wu, Nan, Hu, Sijun, Zhang, Song, Li, Mengbin, Wu, Kaichun, Yang, Xiaoyong, Liang, Jie, Nie, Yongzhan, Fan, Daiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336687/
https://www.ncbi.nlm.nih.gov/pubmed/30093632
http://dx.doi.org/10.1038/s41388-018-0435-5

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