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LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores

Faithful chromosome segregation requires proper chromosome congression at prometaphase and dynamic maintenance of the aligned chromosomes at metaphase. Chromosome missegregation can result in aneuploidy, birth defects and cancer. The kinetochore-bound KMN network and the kinesin motor CENP-E are cri...

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Detalles Bibliográficos
Autores principales:	Wu, Min, Chang, Yan, Hu, Huaibin, Mu, Rui, Zhang, Yucheng, Qin, Xuanhe, Duan, Xiaotao, Li, Weihua, Tu, Haiqing, Zhang, Weina, Wang, Guang, Han, Qiuying, Li, Ailing, Zhou, Tao, Iwai, Kazuhiro, Zhang, Xuemin, Li, Huiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336796/ https://www.ncbi.nlm.nih.gov/pubmed/30655516 http://dx.doi.org/10.1038/s41467-018-08043-7

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