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Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis

We have recently reported an important role of Connexin 43 (Cx43) hemichannels in the pathogenesis of lethal sepsis through facilitating ATP efflux to potentiate the double-stranded RNA-activated protein kinase R (PKR)-dependent macrophage activation. Here we further elucidated the possible role of...

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Detalles Bibliográficos
Autores principales:	Chen, Weiqiang, Zhu, Shu, Wang, Yongjun, Li, Jianhua, Qiang, Xiaoling, Zhao, Xiaoling, Yang, Huan, D’Angelo, John, Becker, Lance, Wang, Ping, Tracey, Kevin J., Wang, Haichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336828/ https://www.ncbi.nlm.nih.gov/pubmed/30655582 http://dx.doi.org/10.1038/s41598-018-37232-z

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