Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

Despite significant progress, our understanding of how specific oncogenes transform cells is still limited and likely underestimates the complexity of downstream signalling events. To address this gap, we use mass spectrometry-based chemical proteomics to characterize the global impact of an oncogen...

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Detalles Bibliográficos
Autores principales: Ma, Xiuquan, Zhang, Luxi, Song, Jiangning, Nguyen, Elizabeth, Lee, Rachel S., Rodgers, Samuel J., Li, Fuyi, Huang, Cheng, Schittenhelm, Ralf B., Chan, Howard, Chheang, Chanly, Wu, Jianmin, Brown, Kristin K., Mitchell, Christina A., Simpson, Kaylene J., Daly, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336867/
https://www.ncbi.nlm.nih.gov/pubmed/30655532
http://dx.doi.org/10.1038/s41467-018-08154-1

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