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Proteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways

Equine myofibrillar myopathy (MFM) causes exertional muscle pain and is characterized by myofibrillar disarray and ectopic desmin aggregates of unknown origin. To investigate the pathophysiology of MFM, we compared resting and 3 h postexercise transcriptomes of gluteal muscle and the resting skeleta...

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Detalles Bibliográficos
Autores principales: Valberg, Stephanie J., Perumbakkam, Sudeep, McKenzie, Erica C., Finno, Carrie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337024/
https://www.ncbi.nlm.nih.gov/pubmed/30289745
http://dx.doi.org/10.1152/physiolgenomics.00044.2018

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