Development of a Transcriptional Amplification System Based on the PEG3 Promoter to Target Androgen Receptor-Positive and -Negative Prostate Cancer Cells

Localized prostate cancer (PCa) is often curable, whereas metastatic disease treated by castration inevitably progresses toward castration-resistant PCa (CRPC). Most CRPC treatments target androgen receptor (AR) signaling. However, not all CRPC cells rely on AR activity for survival and proliferatio...

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Detalles Bibliográficos
Autores principales: Jain, Pallavi, Clermont, Pier-Luc, Desmeules, Francis, Zoubeidi, Amina, Neveu, Bertrand, Pouliot, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337121/
https://www.ncbi.nlm.nih.gov/pubmed/30626088
http://dx.doi.org/10.3390/ijms20010216

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