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New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation

The antitumor activity of natural flavonoids has been exhaustively reported. Previously it has been demonstrated that prenylation of flavonoids allows the discovery of new compounds with improved antitumor activity through the activation of caspase-7 activity. The synthesis of twenty-five flavonoids...

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Detalles Bibliográficos
Autores principales: Moreira, Joana, Ribeiro, Diana, Silva, Patrícia M. A., Nazareth, Nair, Monteiro, Madalena, Palmeira, Andreia, Saraiva, Lucília, Pinto, Madalena, Bousbaa, Hassan, Cidade, Honorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337158/
https://www.ncbi.nlm.nih.gov/pubmed/30602686
http://dx.doi.org/10.3390/molecules24010129