Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event

Asbestos exposure increases the risk of asbestosis and malignant mesothelioma (MM). Both fibrosis and cancer have been correlated with the Epithelial to Mesenchymal Transition (EMT)—an event involved in fibrotic development and cancer progression. During EMT, epithelial cells acquire a mesenchymal p...

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Detalles Bibliográficos
Autores principales: Turini, Stefano, Bergandi, Loredana, Gazzano, Elena, Prato, Mauro, Aldieri, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337211/
https://www.ncbi.nlm.nih.gov/pubmed/30609805
http://dx.doi.org/10.3390/ijms20010150

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