Cargando…

New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism that is associated with most of these risk factors and stressors, and represents an early (subclinical) marker/predict...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daiber, Andreas, Xia, Ning, Steven, Sebastian, Oelze, Matthias, Hanf, Alina, Kröller-Schön, Swenja, Münzel, Thomas, Li, Huige
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337296/ https://www.ncbi.nlm.nih.gov/pubmed/30621010 http://dx.doi.org/10.3390/ijms20010187

Ejemplares similares

Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases
por: Daiber, Andreas, et al.
Publicado: (2020)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Lack of Endothelial α1AMPK Reverses the Vascular Protective Effects of Exercise by Causing eNOS Uncoupling
por: Jansen, Thomas, et al.
Publicado: (2021)

Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system
por: Daiber, Andreas, et al.
Publicado: (2017)

Noise-Induced Vascular Dysfunction, Oxidative Stress, and Inflammation Are Improved by Pharmacological Modulation of the NRF2/HO-1 Axis
por: Bayo Jimenez, Maria Teresa, et al.
Publicado: (2021)

PGC-1α dictates endothelial function through regulation of eNOS expression
por: Craige, Siobhan M., et al.
Publicado: (2016)

Endothelial nitric oxide synthase (eNOS) variants in cardiovascular disease: pharmacogenomic implications
por: Bhanoori, Manjula
Publicado: (2011)

Endothelial Nitric Oxide Synthase (eNOS) and the Cardiovascular System: in Physiology and in Disease States
por: Tran, N, et al.
Publicado: (2022)

The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation
por: Steven, Sebastian, et al.
Publicado: (2018)

Extensive Ethnogenomic Diversity of Endothelial Nitric Oxide Synthase (eNOS) Polymorphisms
por: Thomas, Bolaji N., et al.
Publicado: (2013)

Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease
por: Steven, Sebastian, et al.
Publicado: (2019)

The Adverse Effects of Environmental Noise Exposure on Oxidative Stress and Cardiovascular Risk
por: Münzel, Thomas, et al.
Publicado: (2018)

The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats
por: Steven, Sebastian, et al.
Publicado: (2017)

Development of an Analytical Assay for Electrochemical Detection and Quantification of Protein-Bound 3-Nitrotyrosine in Biological Samples and Comparison with Classical, Antibody-Based Methods
por: Vujacic-Mirski, Ksenija, et al.
Publicado: (2020)

Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth
por: Barbieri, Antonio, et al.
Publicado: (2012)

Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis
por: Boopathy, Gandhi T. K., et al.
Publicado: (2017)

Vascular Redox Signaling, Endothelial Nitric Oxide Synthase Uncoupling, and Endothelial Dysfunction in the Setting of Transportation Noise Exposure or Chronic Treatment with Organic Nitrates
por: Münzel, Thomas, et al.
Publicado: (2023)

Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension
por: Steven, Sebastian, et al.
Publicado: (2017)

Comparison of Mitochondrial Superoxide Detection Ex Vivo/In Vivo by mitoSOX HPLC Method with Classical Assays in Three Different Animal Models of Oxidative Stress
por: Kalinovic, Sanela, et al.
Publicado: (2019)

NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy
por: Brandt, Moritz, et al.
Publicado: (2016)

Association of endothelial nitric oxide synthase (eNOS) polymorphisms with EGFR-mutated lung adenocarcinoma in Taiwan
por: Huang, Chun-Yao, et al.
Publicado: (2018)

Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation
por: Nguyen, Tung D., et al.
Publicado: (2023)

Organic Nitrates and Nitrate Resistance in Diabetes: The Role of Vascular Dysfunction and Oxidative Stress with Emphasis on Antioxidant Properties of Pentaerithrityl Tetranitrate
por: Oelze, Matthias, et al.
Publicado: (2010)

A Pivotal Role for Tryptophan 447 in Enzymatic Coupling of Human Endothelial Nitric Oxide Synthase (eNOS): EFFECTS ON TETRAHYDROBIOPTERIN-DEPENDENT CATALYSIS AND eNOS DIMERIZATION
por: Benson, Matthew A., et al.
Publicado: (2013)

Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension
por: Helmstädter, Johanna, et al.
Publicado: (2020)

Role of Endothelial Nitric Oxide Synthase in Diabetic Nephropathy: Lessons from Diabetic eNOS Knockout Mice
por: Takahashi, Takamune, et al.
Publicado: (2014)

Endothelial Nitric Oxide Synthase (eNOS) 4a/b and G894T Polymorphisms and Susceptibility to Preeclampsia
por: Rahimi, Zohreh, et al.
Publicado: (2013)

Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice
por: Münzel, Thomas, et al.
Publicado: (2017)

Salvianic Acid A Regulates High-Glucose-Treated Endothelial Progenitor Cell Dysfunction via the AKT/Endothelial Nitric Oxide Synthase (eNOS) Pathway
por: Guan, Yanhua, et al.
Publicado: (2021)

Interplay of the red blood cell and vascular endothelial nitric oxide synthase system to combat cardiac complications of anemia
por: Daiber, Andreas, et al.
Publicado: (2020)

Evaluation of Apricot, Bilberry, and Elderberry Pomace Constituents and Their Potential To Enhance the Endothelial Nitric Oxide Synthase (eNOS) Activity
por: Waldbauer, Katharina, et al.
Publicado: (2018)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Phytoestrogenic Effects of Blackcurrant Anthocyanins Increased Endothelial Nitric Oxide Synthase (eNOS) Expression in Human Endothelial Cells and Ovariectomized Rats
por: Horie, Kayo, et al.
Publicado: (2019)

Cigarette Smoke Extract Changes Expression of Endothelial Nitric Oxide Synthase (eNOS) and p16(INK4a) and is Related to Endothelial Progenitor Cell Dysfunction
por: He, Zhihui, et al.
Publicado: (2017)

The AMP-Activated Protein Kinase Plays a Role in Antioxidant Defense and Regulation of Vascular Inflammation
por: Jansen, Thomas, et al.
Publicado: (2020)

Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) rats
por: Grijalva, James, et al.
Publicado: (2008)

The polymorphism G894 T of endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to essential hypertension (EH) in Morocco
por: Nassereddine, Sanaa, et al.
Publicado: (2018)

Endothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells
por: Gao, Weijie, et al.
Publicado: (2022)

Association between endothelial nitric oxide synthase (eNOS) gene variants and nitric oxide production in preeclampsia: a case–control study in Ghana
por: Fondjo, Linda Ahenkorah, et al.
Publicado: (2023)

The Sodium-Glucose Co-Transporter 2 Inhibitor Empagliflozin Improves Diabetes-Induced Vascular Dysfunction in the Streptozotocin Diabetes Rat Model by Interfering with Oxidative Stress and Glucotoxicity
por: Oelze, Matthias, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_atv0vk5bs72ejut5cf102dq5ps