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Hyaluronic Acid Coated Acid-Sensitive Nanoparticles for Targeted Therapy of Adjuvant-Induced Arthritis in Rats

Activated macrophages play a vital role in rheumatoid arthritis (RA) pathophysiology. CD44 is an overexpressed receptor on activated macrophages that is a potential target site for RA treatment. In this study, we prepared hyaluronic acid (HA) coated acid-sensitive polymeric nanoparticles (HAPNPs) co...

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Detalles Bibliográficos
Autores principales: Yu, Changhui, Li, Xiangyu, Hou, Yufei, Meng, Xiangxue, Wang, Deli, Liu, Jiaxin, Sun, Fengying, Li, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337373/
https://www.ncbi.nlm.nih.gov/pubmed/30609724
http://dx.doi.org/10.3390/molecules24010146