Cargando…

In Vitro Induction of Tendon-Specific Markers in Tendon Cells, Adipose- and Bone Marrow-Derived Stem Cells is Dependent on TGFβ3, BMP-12 and Ascorbic Acid Stimulation

Mesenchymal Stem Cells (MSCs) and tissue-specific progenitors have been proposed as useful tools for regenerative medicine approaches in bone, cartilage and tendon-related pathologies. The differentiation of cells towards the desired, target tissue-specific lineage has demonstrated advantages in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perucca Orfei, Carlotta, Viganò, Marco, Pearson, John R., Colombini, Alessandra, De Luca, Paola, Ragni, Enrico, Santos-Ruiz, Leonor, de Girolamo, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337430/ https://www.ncbi.nlm.nih.gov/pubmed/30609804 http://dx.doi.org/10.3390/ijms20010149

Ejemplares similares

Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation
por: Viganò, Marco, et al.
Publicado: (2019)

A(2A) adenosine receptors are involved in the reparative response of tendon cells to pulsed electromagnetic fields
por: Colombini, Alessandra, et al.
Publicado: (2020)

Secreted Factors and EV-miRNAs Orchestrate the Healing Capacity of Adipose Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis
por: Ragni, Enrico, et al.
Publicado: (2020)

Different culture conditions affect the growth of human tendon stem/progenitor cells (TSPCs) within a mixed tendon cells (TCs) population
por: Viganò, M., et al.
Publicado: (2017)

miR-103a-3p and miR-22-5p Are Reliable Reference Genes in Extracellular Vesicles From Cartilage, Adipose Tissue, and Bone Marrow Cells
por: Ragni, Enrico, et al.
Publicado: (2021)

Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs
por: Ragni, Enrico, et al.
Publicado: (2021)

Characterization of Microfragmented Adipose Tissue Architecture, Mesenchymal Stromal Cell Content and Release of Paracrine Mediators
por: Ragni, Enrico, et al.
Publicado: (2022)

Reliable Reference Genes for Gene Expression Assessment in Tendon-Derived Cells under Inflammatory and Pro-Fibrotic/Healing Stimuli
por: Ragni, Enrico, et al.
Publicado: (2019)

Identification of miRNA Reference Genes in Extracellular Vesicles from Adipose Derived Mesenchymal Stem Cells for Studying Osteoarthritis
por: Ragni, Enrico, et al.
Publicado: (2019)

Endogenous Controls for the Evaluation of Osteoarthritis-Related miRNAs in Extracellular Vesicles from Bone-Marrow-Derived Mesenchymal Stromal Cells and the Impact of Osteoarthritis Synovial Fluid
por: Ragni, Enrico, et al.
Publicado: (2022)

Adipose-Derived Mesenchymal Stromal Cells Treated with Interleukin 1 Beta Produced Chondro-Protective Vesicles Able to Fast Penetrate in Cartilage
por: Colombini, Alessandra, et al.
Publicado: (2021)

Insights into Inflammatory Priming of Adipose-Derived Mesenchymal Stem Cells: Validation of Extracellular Vesicles-Embedded miRNA Reference Genes as A Crucial Step for Donor Selection
por: Ragni, Enrico, et al.
Publicado: (2019)

Secreted Factors and Extracellular Vesicles Account for the Immunomodulatory and Tissue Regenerative Properties of Bone-Marrow-Derived Mesenchymal Stromal Cells for Osteoarthritis
por: Ragni, Enrico, et al.
Publicado: (2022)

Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease
por: Ragni, Enrico, et al.
Publicado: (2020)

Evaluation of Different Seeding Methods for Cell-Seeded Collagen Matrix-Supported Autologous Chondrocyte Transplantation
por: Viganò, Marco, et al.
Publicado: (2019)

miRNA Reference Genes in Extracellular Vesicles Released from Amniotic Membrane-Derived Mesenchymal Stromal Cells
por: Ragni, Enrico, et al.
Publicado: (2020)

Human Tendon Stem/Progenitor Cell Features and Functionality Are Highly Influenced by in vitro Culture Conditions
por: Perucca Orfei, Carlotta, et al.
Publicado: (2021)

In Vitro Study of Extracellular Vesicles Migration in Cartilage-Derived Osteoarthritis Samples Using Real-Time Quantitative Multimodal Nonlinear Optics Imaging
por: Mortati, Leonardo, et al.
Publicado: (2020)

Molecular Characterization of Secreted Factors and Extracellular Vesicles-Embedded miRNAs from Bone Marrow-Derived Mesenchymal Stromal Cells in Presence of Synovial Fluid from Osteoarthritis Patients
por: Ragni, Enrico, et al.
Publicado: (2022)

Amniotic membrane‐mesenchymal stromal cells secreted factors and extracellular vesicle‐miRNAs: Anti‐inflammatory and regenerative features for musculoskeletal tissues
por: Ragni, Enrico, et al.
Publicado: (2021)

Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes
por: Ragni, Enrico, et al.
Publicado: (2019)

Joint Tissue Protective and Immune-Modulating miRNA Landscape of Mesenchymal Stromal Cell-Derived Extracellular Vesicles under Different Osteoarthritis-Mimicking Conditions
por: Ragni, Enrico, et al.
Publicado: (2022)

High-Throughput Gene and Protein Analysis Revealed the Response of Disc Cells to Vitamin D, Depending on the VDR FokI Variants
por: Colombini, Alessandra, et al.
Publicado: (2021)

The effects of orthobiologics in the treatment of tendon pathologies: a systematic review of preclinical evidence
por: Viganò, Marco, et al.
Publicado: (2022)

Tissue-Protective and Anti-Inflammatory Landmark of PRP-Treated Mesenchymal Stromal Cells Secretome for Osteoarthritis
por: Ragni, Enrico, et al.
Publicado: (2022)

Silk/Fibroin Microcarriers for Mesenchymal Stem Cell Delivery: Optimization of Cell Seeding by the Design of Experiment
por: Perucca Orfei, Carlotta, et al.
Publicado: (2018)

Vitamin D’s Effect on the Proliferation and Inflammation of Human Intervertebral Disc Cells in Relation to the Functional Vitamin D Receptor Gene FokI Polymorphism
por: De Luca, Paola, et al.
Publicado: (2018)

The Effect of Three Different Suture Anchors for Rotator Cuff Repair on Primary Cultures of Human Bone Marrow Mesenchymal Stem Cells
por: Thiébat, Gabriele, et al.
Publicado: (2018)

Treatment of Achilles Tendinopathy with Autologous Adipose-derived Stromal Vascular Fraction: Results of a Randomized Prospective Clinical Trial
por: de Girolamo, Laura, et al.
Publicado: (2016)

Human Diseased Articular Cartilage Contains a Mesenchymal Stem Cell-Like Population of Chondroprogenitors with Strong Immunomodulatory Responses
por: De Luca, Paola, et al.
Publicado: (2019)

Innovative Visualization and Quantification of Extracellular Vesicles Interaction with and Incorporation in Target Cells in 3D Microenvironments
por: Ragni, Enrico, et al.
Publicado: (2020)

Effects of the pulsed electromagnetic field PST® on human tendon stem cells: a controlled laboratory study
por: Randelli, Pietro, et al.
Publicado: (2016)

Mesenchymal stem cells as therapeutic target of biophysical stimulation for the treatment of musculoskeletal disorders
por: Viganò, Marco, et al.
Publicado: (2016)

High Levels of Circulating Type II Collagen Degradation Marker (CTx-II) Are Associated with Specific VDR Polymorphisms in Patients with Adult Vertebral Osteochondrosis
por: Cauci, Sabina, et al.
Publicado: (2017)

Superior Osteo-Inductive and Osteo-Conductive Properties of Trabecular Titanium vs. PEEK Scaffolds on Human Mesenchymal Stem Cells: A Proof of Concept for the Use of Fusion Cages
por: Ragni, Enrico, et al.
Publicado: (2021)

Treatment with Human Amniotic Suspension Allograft Improves Tendon Healing in a Rat Model of Collagenase-Induced Tendinopathy
por: de Girolamo, Laura, et al.
Publicado: (2019)

TGFβ1-transfected tendon stem cells promote tendon fibrosis
por: Yu, Hong-Bin, et al.
Publicado: (2022)

Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging
por: Dai, Guangchun, et al.
Publicado: (2020)

Cell-based therapies have disease-modifying effects on osteoarthritis in animal models. A systematic review by the ESSKA Orthobiologic Initiative. Part 2: bone marrow-derived cell-based injectable therapies
por: Boffa, Angelo, et al.
Publicado: (2023)

Cell-based therapies have disease-modifying effects on osteoarthritis in animal models. A systematic review by the ESSKA Orthobiologic Initiative. Part 1: adipose tissue-derived cell-based injectable therapies
por: Perucca Orfei, Carlotta, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s2hfnoau8j4g91oar19717ero5