Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substit...

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Detalles Bibliográficos
Autores principales: Tian, Qingqiang, Luo, Wen, Gan, Zongjie, Li, Dan, Dai, Zeshu, Wang, Huajun, Wang, Xuetong, Yuan, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337447/
https://www.ncbi.nlm.nih.gov/pubmed/30621218
http://dx.doi.org/10.3390/molecules24010174
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author Tian, Qingqiang
Luo, Wen
Gan, Zongjie
Li, Dan
Dai, Zeshu
Wang, Huajun
Wang, Xuetong
Yuan, Jianyong
author_facet Tian, Qingqiang
Luo, Wen
Gan, Zongjie
Li, Dan
Dai, Zeshu
Wang, Huajun
Wang, Xuetong
Yuan, Jianyong
author_sort Tian, Qingqiang
collection PubMed
description A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substituted benzoxazoles and 2-substituted benzothiazoles were thus prepared in moderate to excellent yields.
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spelling pubmed-63374472019-01-25 Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride Tian, Qingqiang Luo, Wen Gan, Zongjie Li, Dan Dai, Zeshu Wang, Huajun Wang, Xuetong Yuan, Jianyong Molecules Article A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substituted benzoxazoles and 2-substituted benzothiazoles were thus prepared in moderate to excellent yields. MDPI 2019-01-04 /pmc/articles/PMC6337447/ /pubmed/30621218 http://dx.doi.org/10.3390/molecules24010174 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tian, Qingqiang
Luo, Wen
Gan, Zongjie
Li, Dan
Dai, Zeshu
Wang, Huajun
Wang, Xuetong
Yuan, Jianyong
Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title_full Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title_fullStr Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title_full_unstemmed Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title_short Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles from 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride
title_sort eco-friendly syntheses of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and dmf derivatives in the presence of imidazolium chloride
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337447/
https://www.ncbi.nlm.nih.gov/pubmed/30621218
http://dx.doi.org/10.3390/molecules24010174
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