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Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications

This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent...

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Detalles Bibliográficos
Autores principales: Albuquerque, Hélio M. T., Santos, Clementina M. M., Silva, Artur M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337470/
https://www.ncbi.nlm.nih.gov/pubmed/30597999
http://dx.doi.org/10.3390/molecules24010116
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author Albuquerque, Hélio M. T.
Santos, Clementina M. M.
Silva, Artur M. S.
author_facet Albuquerque, Hélio M. T.
Santos, Clementina M. M.
Silva, Artur M. S.
author_sort Albuquerque, Hélio M. T.
collection PubMed
description This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds.
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spelling pubmed-63374702019-01-25 Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications Albuquerque, Hélio M. T. Santos, Clementina M. M. Silva, Artur M. S. Molecules Review This review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds. MDPI 2018-12-29 /pmc/articles/PMC6337470/ /pubmed/30597999 http://dx.doi.org/10.3390/molecules24010116 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Albuquerque, Hélio M. T.
Santos, Clementina M. M.
Silva, Artur M. S.
Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title_full Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title_fullStr Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title_full_unstemmed Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title_short Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
title_sort cholesterol-based compounds: recent advances in synthesis and applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337470/
https://www.ncbi.nlm.nih.gov/pubmed/30597999
http://dx.doi.org/10.3390/molecules24010116
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