Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma

Cancer stem cells (CSCs) have been shown as a distinct population of cancer cells strongly implicated with resistance to conventional chemotherapy. Metformin, the most widely prescribed drug for diabetes, was reported to target cancer stem cells in various cancers. In this study, we sought to determ...

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Detalles Bibliográficos
Autores principales: Kuo, Selena Z., Honda, Christine O., Li, Wei Tse, Honda, Thomas K., Kim, Elizabeth, Altuna, Xabier, Abhold, Eric, Wang-Rodriguez, Jessica, Ongkeko, Weg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337486/
https://www.ncbi.nlm.nih.gov/pubmed/30621095
http://dx.doi.org/10.3390/ijms20010193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337486/
https://www.ncbi.nlm.nih.gov/pubmed/30621095
http://dx.doi.org/10.3390/ijms20010193

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