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Optimization of Extended-Release ZL-004 Nanosuspensions for In Vivo Pharmacokinetic Study to Enhance Low Solubility and Compliance

ZL-004, a promising small molecule that increases white blood cell counts, was developed for extended-release nanosuspensions to improve low solubility and compliance of patients. In vivo pharmacokinetic studies of nanosuspensions with different particle sizes and administration volumes were conduct...

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Detalles Bibliográficos
Autores principales:	Guo, Chengyue, Chen, Yanna, Zhu, Junzhe, Wang, Jiaxin, Xu, Ying, Luan, Hansen, Wang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337511/ https://www.ncbi.nlm.nih.gov/pubmed/30577480 http://dx.doi.org/10.3390/molecules24010007

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