Gemcitabine Induces Microvesicle Particle Release in a Platelet-Activating Factor-Receptor-Dependent Manner via Modulation of the MAPK Pathway in Pancreatic Cancer Cells

Studies, including ours, have shown that pro-oxidative stressors, such as chemotherapeutic agents, generate oxidized lipids with agonistic platelet-activating factor (PAF) activity. Importantly, recent reports have implicated that these PAF-agonists are transported extracellularly via microvesicle p...

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Detalles Bibliográficos
Autores principales: Thyagarajan, Anita, Kadam, Sayali M., Liu, Langni, Kelly, Lisa E., Rapp, Christine M., Chen, Yanfang, Sahu, Ravi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337552/
https://www.ncbi.nlm.nih.gov/pubmed/30577630
http://dx.doi.org/10.3390/ijms20010032

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