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Synthetic Tyrosine tRNA Molecules with Noncanonical Secondary Structures
The L-shape form of tRNA is maintained by tertiary interactions occurring in the core. Base changes in this domain can cause structural defects and impair tRNA activity. Here, we report on a method to safely engineer structural variations in this domain utilizing the noncanonical scaffold of tRNA(Py...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337575/ https://www.ncbi.nlm.nih.gov/pubmed/30587834 http://dx.doi.org/10.3390/ijms20010092 |