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Topical Application of TGF-β-Activating Peptide, KRFK, Prevents Inflammatory Manifestations in the TSP-1-Deficient Mouse Model of Chronic Ocular Inflammation

Chronic inflammation of the ocular surface poses a risk of vision impairment. The understanding of the molecular mechanisms that are involved in the inflammatory response is critical to identify novel molecular targets. Recently, thrombospondin-1 (TSP-1) has emerged as a key player in ocular surface...

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Detalles Bibliográficos
Autores principales: Soriano-Romaní, Laura, Contreras-Ruiz, Laura, López-García, Antonio, Diebold, Yolanda, Masli, Sharmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337581/
https://www.ncbi.nlm.nih.gov/pubmed/30577496
http://dx.doi.org/10.3390/ijms20010009