A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies

In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to...

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Detalles Bibliográficos
Autores principales: Borcea, Anca-Maria, Marc, Gabriel, Ionuț, Ioana, Vodnar, Dan C., Vlase, Laurian, Gligor, Felicia, Pricopie, Andreea, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337626/
https://www.ncbi.nlm.nih.gov/pubmed/30621322
http://dx.doi.org/10.3390/molecules24010184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337626/
https://www.ncbi.nlm.nih.gov/pubmed/30621322
http://dx.doi.org/10.3390/molecules24010184

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