Cargando…
A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies
In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to...
Autores principales: | Borcea, Anca-Maria, Marc, Gabriel, Ionuț, Ioana, Vodnar, Dan C., Vlase, Laurian, Gligor, Felicia, Pricopie, Andreea, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337626/ https://www.ncbi.nlm.nih.gov/pubmed/30621322 http://dx.doi.org/10.3390/molecules24010184 |
Ejemplares similares
-
Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin
por: Pricopie, Andreea-Iulia, et al.
Publicado: (2019) -
Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors
por: Stana, Anca, et al.
Publicado: (2017) -
Synthesis of New Phenolic Derivatives of Quinazolin-4(3H)-One as Potential Antioxidant Agents—In Vitro Evaluation and Quantum Studies
por: Pele, Raluca, et al.
Publicado: (2022) -
Novel 2,4-Disubstituted-1,3-Thiazole Derivatives: Synthesis, Anti-Candida Activity Evaluation and Interaction with Bovine Serum Albumine
por: Pricopie, Andreea-Iulia, et al.
Publicado: (2020) -
Development of new 5-(chromene-3-yl)methylene-2,4-thiazolidinediones as antimicrobial agents
por: NASTASĂ, CRISTINA MARIANA, et al.
Publicado: (2016)