Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome

DNA repair processes are involved in both the onset and treatment efficacy of colorectal cancer (CRC). A change of a single nucleotide causing an amino acid substitution in the corresponding protein may alter the efficiency of DNA repair, thus modifying the CRC susceptibility and clinical outcome. W...

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Detalles Bibliográficos
Autores principales: Jiraskova, Katerina, Hughes, David J., Brezina, Stefanie, Gumpenberger, Tanja, Veskrnova, Veronika, Buchler, Tomas, Schneiderova, Michaela, Levy, Miroslav, Liska, Vaclav, Vodenkova, Sona, Di Gaetano, Cornelia, Naccarati, Alessio, Pardini, Barbara, Vymetalkova, Veronika, Gsur, Andrea, Vodicka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337670/
https://www.ncbi.nlm.nih.gov/pubmed/30591675
http://dx.doi.org/10.3390/ijms20010097

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