NFκB Inhibition Mitigates Serum Amyloid A-Induced Pro-Atherogenic Responses in Endothelial Cells and Leukocyte Adhesion and Adverse Changes to Endothelium Function in Isolated Aorta

The acute phase protein serum amyloid A (SAA) is associated with endothelial dysfunction and early-stage atherogenesis. Stimulation of vascular cells with SAA increases gene expression of pro-inflammation cytokines and tissue factor (TF). Activation of the transcription factor, nuclear factor kappa-...

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Detalles Bibliográficos
Autores principales: Vallejo, Abigail, Chami, Belal, Dennis, Joanne M., Simone, Martin, Ahmad, Gulfam, Abdo, Adrian I., Sharma, Arpeeta, Shihata, Waled A., Martin, Nathan, Chin-Dusting, Jaye P. F., de Haan, Judy B., Witting, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337750/
https://www.ncbi.nlm.nih.gov/pubmed/30597899
http://dx.doi.org/10.3390/ijms20010105

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