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Engineering the flagellar type III secretion system: improving capacity for secretion of recombinant protein

BACKGROUND: Many valuable biopharmaceutical and biotechnological proteins have been produced in Escherichia coli, however these proteins are almost exclusively localised in the cytoplasm or periplasm. This presents challenges for purification, i.e. the removal of contaminating cellular constituents....

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Detalles Bibliográficos
Autores principales:	Green, Charlotte A., Kamble, Nitin S., Court, Elizabeth K., Bryant, Owain J., Hicks, Matthew G., Lennon, Christopher, Fraser, Gillian M., Wright, Phillip C., Stafford, Graham P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337784/ https://www.ncbi.nlm.nih.gov/pubmed/30657054 http://dx.doi.org/10.1186/s12934-019-1058-4

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