Coatings on mammalian cells: interfacing cells with their environment

The research community is intent on harnessing increasingly complex biological building blocks. At present, cells represent a highly functional component for integration into higher order systems. In this review, we discuss the current application space for cellular coating technologies and emphasiz...

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Autores principales: Davis, Kara A., Wu, Pei-Jung, Cahall, Calvin F., Li, Cong, Gottipati, Anuhya, Berron, Brad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337841/
https://www.ncbi.nlm.nih.gov/pubmed/30675178
http://dx.doi.org/10.1186/s13036-018-0131-6
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author Davis, Kara A.
Wu, Pei-Jung
Cahall, Calvin F.
Li, Cong
Gottipati, Anuhya
Berron, Brad J.
author_facet Davis, Kara A.
Wu, Pei-Jung
Cahall, Calvin F.
Li, Cong
Gottipati, Anuhya
Berron, Brad J.
author_sort Davis, Kara A.
collection PubMed
description The research community is intent on harnessing increasingly complex biological building blocks. At present, cells represent a highly functional component for integration into higher order systems. In this review, we discuss the current application space for cellular coating technologies and emphasize the relationship between the target application and coating design. We also discuss how the cell and the coating interact in common analytical techniques, and where caution must be exercised in the interpretation of results. Finally, we look ahead at emerging application areas that are ideal for innovation in cellular coatings. In all, cellular coatings leverage the machinery unique to specific cell types, and the opportunities derived from these hybrid assemblies have yet to be fully realized.
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spelling pubmed-63378412019-01-23 Coatings on mammalian cells: interfacing cells with their environment Davis, Kara A. Wu, Pei-Jung Cahall, Calvin F. Li, Cong Gottipati, Anuhya Berron, Brad J. J Biol Eng Review The research community is intent on harnessing increasingly complex biological building blocks. At present, cells represent a highly functional component for integration into higher order systems. In this review, we discuss the current application space for cellular coating technologies and emphasize the relationship between the target application and coating design. We also discuss how the cell and the coating interact in common analytical techniques, and where caution must be exercised in the interpretation of results. Finally, we look ahead at emerging application areas that are ideal for innovation in cellular coatings. In all, cellular coatings leverage the machinery unique to specific cell types, and the opportunities derived from these hybrid assemblies have yet to be fully realized. BioMed Central 2019-01-17 /pmc/articles/PMC6337841/ /pubmed/30675178 http://dx.doi.org/10.1186/s13036-018-0131-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Davis, Kara A.
Wu, Pei-Jung
Cahall, Calvin F.
Li, Cong
Gottipati, Anuhya
Berron, Brad J.
Coatings on mammalian cells: interfacing cells with their environment
title Coatings on mammalian cells: interfacing cells with their environment
title_full Coatings on mammalian cells: interfacing cells with their environment
title_fullStr Coatings on mammalian cells: interfacing cells with their environment
title_full_unstemmed Coatings on mammalian cells: interfacing cells with their environment
title_short Coatings on mammalian cells: interfacing cells with their environment
title_sort coatings on mammalian cells: interfacing cells with their environment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337841/
https://www.ncbi.nlm.nih.gov/pubmed/30675178
http://dx.doi.org/10.1186/s13036-018-0131-6
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