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Emerging roles of telomeric chromatin alterations in cancer

Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the specific complex named shelterin and a tight nuc...

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Detalles Bibliográficos
Autores principales: Cacchione, Stefano, Biroccio, Annamaria, Rizzo, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337846/
https://www.ncbi.nlm.nih.gov/pubmed/30654820
http://dx.doi.org/10.1186/s13046-019-1030-5

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